الفورتيوكستين أحد مضادات الاكتئاب، يصنف من أدوية مثبطات استرداد السيروتونين الانتقائية، حيث يعمل على تثبيط امتصاص السيروتونين الانتقائي في الدماغ، مما يعمل على إعادة توازن النواقل العصبية.
يستخدم هذا الدواء للتخفيف من الآلام الحادة والمزمنة (على سبيل المثال الألم بعد العملية أو آلام الأسنان أو المفاصل أو العضلات.
لا يتعارض استعمال جريبكسون مع اي من هذه الادوية ولكن استعمال لامكتال مع ديباكين يمكن ان يؤدي الى اثار جانبية لذا يجب اخذها معا تحت اشراف الطبيب.
For clients on prior opioid therapy, begin OPANA ER at 50% reduce compared to beginning dose for just a more youthful client on prior opioids and titrate slowly.
الشعور بالدوخة أو الدوار أو التوتر أو الإغماء, انخفاض في ضغط الدم, جفاف الفم, صعوبة في التبول, النعاس, خدر أو وخز في الأطراف.
Your medical doctor could alter your dose as needed. Youngsters—Use and dose must be based on your physician. For oral dosage sort (tablets): For reasonable to intense agony: For people who are not taking narcotic medicines: Older people—To start with, ten to 20 milligrams (mg) each individual 4 to 6 several hours a day. Your health practitioner may possibly modify your dose as needed. Children—Use just isn't recommended. For individuals switching from oxymorphone injection to Opana®: Adults—At the beginning, the dose is 10 situations the full oxymorphone injection dose that you're getting every day, divided into four to 6 equivalent doses. Your health care provider may possibly adjust your dose as desired. Kids—Use is just not advised. For people switching from oral opioids to Opana®: Older people—In the beginning, the dose is half of the total each day dose you are using each day, divided into four to six equal doses, each individual four to 6 several hours. Your medical doctor may change your dose as wanted. Children—Use will not be recommended. Skipped Dose For those who pass up a dose of this drugs, skip the missed dose and return to your normal dosing plan. Don't double doses.
Advise people of the potential risk of everyday living-threatening respiratory melancholy, افضل وقت لاخذ q10 including information that the chance is greatest when starting off OPANA ER or once the dosage is greater, Which it could possibly happen even at advisable doses.
فيما يلي أهم التحذيرات التي يجب الأخذ بها قبل تناول دواء دولوكستين:
Official research around the distribution of oxymorphone in various tissues have not been carried out. Oxymorphone just isn't thoroughly certain to human plasma proteins; binding is within the range of 10% to 12%.
دواء يعمل على علاج الألم التي تسببها العصاب (الاعتلال العصبي )
The safety of OPANA ER was evaluated in a total of 2011 clients in open up-label and controlled medical trials. The scientific trials enrolled of people with reasonable to serious chronic non-malignant soreness, most cancers ache, and publish-surgical discomfort.
In feminine rats, a rise in the duration of your estrus cycle and decrease within the indicate amount of feasible embryos, implantation web pages and corpora lutea ended up observed at 4.9 instances the human dose of 20 mg/day. No adverse results of oxymorphone on male reproductive perform or sperm parameters have been observed.
Opioids are sought for nonmedical use and are issue to diversion from authentic prescribed use. Look at these pitfalls when prescribing or dispensing OPANA ER. Techniques to cut back these challenges contain prescribing the drug inside the smallest suitable quantity and advising the affected person on cautious storage with the drug throughout the program of treatment and correct disposal of unused drug.
Tolerance is actually a physiological condition characterised by a lowered response to some drug just after recurring administration (i.e., a higher dose of a drug is necessary to produce the exact same outcome which was once obtained at a reduce dose).